Around the time "Friends" ended its seven-season run in 2004, Jennifer Aniston was Hollywood's golden girl.
Her rom-com blockbusters "Along Came Polly" and "Bruce Almighty" performed well with critics and in theaters. The latter, headlined by Jim Carrey, raked in $484 million worldwide.
Then an unfortunate string of flops began — enough to earn Aniston the label "box office poison."
Her latest movie, "We're the Millers," about a group of misfits who pose as an all-American family to move a large shipment of marijuana into the U.S., may give Aniston's movie career the second wind it needs.
Co-starring Jason Sudeikis, Emma Roberts, and Ed Helms, "We're the Millers" opened in theaters late Tuesday night and racked up $6.8 million so far. Despite less than thrilling reviews from critics, it's expected to gross between $35 and $38 million through the weekend.
Here are the misses that led up to Aniston's "We're the Millers" redemption.
7. "Derailed" (2005)

Worldwide Lifetime Gross:$57 million
Production Budget:$22 million
Gain: $35 million
Rotten Tomatoes score:20%
Aniston appeared alongside Clive Owen in this psychological thriller about a love affair gone wrong.
With a ludicrous plot and obvious twist, "'Derailed' is an uncomfortably appropriate title,"one critic wrote.
6. "The Switch" (2010)

Worldwide Lifetime Gross:$49 million
Production Budget:$19 million
Gain: $30 million
Rotten Tomatoes score:51%
Aniston plays a character with no husband or boyfriend, who's fighting the clock to have children. Jason Bateman co-stars.
To put into perspective how bad it was, a "Twilight" parody movie beat it at the box office.
5. "Love Happens" (2009)

Worldwide Lifetime Gross:$36 million
Production Budget:$18 million
Gain: $18 million
Rotten Tomatoes score:17%
The author of a self-help book about grieving (Aaron Eckhart) falls for a florist (Aniston) while dealing with the loss of his wife.
The New York Times called the movie's vital signs, "faint."
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